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Hematogenous Osteomyelitis in
Infants and Children: Imaging of a
Changing Disease
Autor: Diego Jaramillo, MD, MPH, John P. Dormans, MD, Jorge Delgado, MD, Tal Laor, MD, Joseph W. St. Geme III, MD
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In children, hematogenous osteomyelitis is an infection
that primarily affects the most vascularized regions of the
growing skeleton. The disease has increased in frequency,
virulence, and degree of soft-tissue involvement. The
change in clinical manifestations and management over
the past 2 decades should be reflected in the current
imaging approach to the disease. Imaging of infection
must depict the location of a single focus or of multiple
foci of involvement and the presence of drainable collections.
This review provides an overview of the imaging
implications directed by the changing epidemiology, the
newer insights of anatomy and pathophysiology, the imaging
characteristics with emphasis on specific locations
and disease complications, and the differential diagnosis
considerations. In addition, basic imaging guidelines for
appropriate extent of area to image based on patient age
are provided.
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Multiparametric magnetic resonance imaging
(MRI) is essential in the evaluation of sonographically
indeterminate adnexal lesions, because it
enables an adequate characterization of these lesions
and their classification based on the degree
of suspicion for malignancy. It also allows the
most accurate therapy and/or follow-up approach,
limiting the associated costs.
The majority of indeterminate adnexal lesions
at ultrasound are benign and its characterization
with MRI avoids unnecessary and inappropriate
surgery. Only a minority of these lesions corresponds
to malignant adnexal disease, and their
proper evaluation by MRI allows timely implementation
of the correct therapeutic approach,
which is the key aspect in the management of
these tumors.
In this article the authors review and illustrate the
MRI characteristics of the sonographically indeterminate
adnexal lesions, which classifies them
attending to their degree of suspicion. The multiparametric
MRI protocol that should be applied
in the study of these tumors is also highlighted.
Key-words:
Adnexal Diseases; Ultrasound; Magnetic
Resonance; Classification.
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